Semax
A lab-made peptide built from a piece of a natural stress hormone, studied for focus, mood, and brain-protection signals.
Learn about SemaxWellness & vitality
Selank
A lab-made peptide based on a natural immune fragment, studied in Russia for calm focus without the drowsiness of a sedative.
- Origin
- Based on tuftsin
- Type
- Lab-made peptide
- Category
- Wellness & vitality
- FDA status
- Not FDA-approved
Overview
What it is
Selank is a lab-made peptide based on tuftsin, a short natural peptide involved in immune signaling. It was developed and studied largely in Russia.
Selank was developed at a Russian research institute in the 1990s, alongside semax. Both were designed as peptide alternatives to conventional medicines.
Its starting point is tuftsin, a four-amino-acid piece of an antibody that helps immune cells do their job. Selank adds a short tail so it survives longer in the body.
It is registered as a medicine in Russia for anxiety. It has never been through FDA review, and its trials have not been repeated by independent groups elsewhere.
Benefits
What it supports
- Supports a calmer response to stress without a heavy, sedated feeling
- Supports focus and memory when the pressure is on
- Supports mood-resilience goals
- Supports immune-signaling pathways it inherits from tuftsin
Mechanism
How it works
1
GABA is the brain's main calming signal. Most anti-anxiety medicines work by strengthening it, which is also why many of them cause drowsiness and dependence.
2
Selank appears to influence that same system, but indirectly and more gently. Russian studies report a calming effect without heavy sedation.
3
It also seems to slow the breakdown of enkephalins, the body's own natural calming and pain-relieving molecules, so they stay around longer.
4
Because it comes from an immune peptide, some studies also look at immune signaling. That is a secondary theme rather than the main one.
Context
Who it's for
Adults looking for a calmer stress response without a heavy or sedated feeling
People who want to keep their focus sharp during high-pressure stretches
Adults interested in mood resilience
People comparing selank with semax, since the two are usually mentioned together
Landscape
In the landscape
How this compound compares to related options in the wellness landscape.
In this area
Related therapies
Other compounds that support overlapping wellness goals.
Questions
Selank FAQ
Good to know
Regulatory & considerations
Selank is not FDA-approved. That means the FDA has not reviewed it for safety or effectiveness for the uses described here. It is a registered medicine in Russia, but the FDA has not reviewed it and its trials have not been repeated elsewhere.
Peptides in our shop are sourced from US-licensed manufacturers.
Selank is not FDA-approved. It is a registered medicine in Russia, but that approval does not carry over.
Its trials come almost entirely from its country of origin and have not been independently repeated.
Ongoing anxiety has treatments with strong evidence behind them. A peptide is not a substitute for that conversation.
Shop Selank
See current pricing and availability for Selank in our shop. If a medical evaluation is needed, a licensed provider guides you through it.
Individual results vary. General information on this site is not a substitute for professional medical advice.